Nutrition, Brain Aging, and
Neurodegeneration

The Journal of Neuroscience, October 14, 2009. 29(41):12795-12801.12795

James Joseph, Greg Cole, Elizabeth Head, and Donald Ingram.
USDA Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts 02111, Geriatric Research, Education and Clinical Centers, Veterans Affairs Medical Center, and Department of Medicine, University of California, Los Angeles, Sepulveda, California 91343, University of Kentucky Sanders-Brown Center on Aging, Lexington, Kentucky 40536, and Pennington Biomedical Center, Baton Rouge, Louisiana 70808

Together, the findings provide compelling evidence to suggest lifestyle changes involving caloric selection through alterations in berry fruit, nut, fish oil, and curcumin intake, and caloric restriction may provide beneficial effects in aging and prevent or delay the onset of neurodegenerative diseases such as AD. These changes may provide the most efficacious methods thus far for increasing “health span.” Interestingly, while many of the mechanisms for the beneficial effects of these nutritional interventions have yet to be discerned, it is clear that they involve decreases in oxidative/inflammatory stress signaling, increases in protective signaling, and may even involve effects to protect against the two major villains of aging, oxidative and inflammatory stressors.​

​Vegetables, and spices, or even reduced caloric intake, may lower age-related cognitive declines and the risk of developing neurodegenerative disease.

It is important to determine what methods can be used today to increase healthy aging, forestall the onset of age-related diseases, and create conditions favorable to obtaining a “longevity dividend.” Recent studies suggest that consumption of diets rich in antioxidants and anti-inflammatory components such as those found in fruits, nuts,

OxyNaturals® Comment: All of our nutriceuticals, especially OxySpark, OxyBoost and MemNivia contain anti-inflammatory/anti-oxidative ingredients and as such are very effective in increasing the "health span" of the aging population.

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