SLEEP's Active Ingredient Lemon Verbena Extract, Extracted and Purified in a Patented Process, is a "Natural Solution to Help Individuals Improve Their Stress and Sleep Quality"

Nutrients, 2022 Jan 4. "Anxiolytic Effect and Improved Sleep Quality in Individuals Taking Lippia citriodora
Extract. " Published By the National Center for Biotechnology Information

New, Patented Clinically Proven All-Natural Sleep Aid Formulated to Help You Relax, Fall Asleep Faster, Stay Asleep Longer and Awake Refreshed and Renewed

SLEEP's Active Ingredient RelaxPLX® Increases Your Brain's Sensitivity to GABA — A Central Nervous System Neurotransmitter Responsible for Reducing Stress and Anxiety, While Promoting Deep Sleep. It Also Increases Serotonin, Norepinephrine & Dopamine for Refreshed Waking, Morning Energy & Renewal.

Clinically proven to improve anxiety and sleep quality, with lower cortisol levels,
fewer interruptions while sleeping, more time in deep sleep and a tendency to increase REM.

7

Years of Research

15

Scientific Journals

6

Clinical Studies

Key Concepts/Summary

(All You Need to Know About OxyNaturals®' SLEEP)

  • Active Ingredient: SLEEP's active ingredient RelaxPLX® is produced through a patented process that extracts and purifies nutrients (phenylpropanoids/verbascoside and flavones) from the Lemon Verbena plant. Sleep PLX® has been scientifically proven to have significant benefi­cial effects on stress, anxiety and insomnia symptoms. 
  • ​Mechanism of Action: RelaxPLX's® mechanism of action (how it works) is in how it may affect neurotransmitters in the brain — chemicals that nerves release to communicate with other nearby nerves. One of these neurotransmitters is gamma-amino-butyric acid (GABA), a neurotransmitter that suppresses the activity of nerves. Excessive activity of nerves can be a cause of anxiety and insomnia. RelaxPLX® helps support the reduction of the activity of nerves in the brain and spinal cord by enhancing the effects of GABA and thus reducing anxiety and promoting sleep.
  • ​Proven in 6 Clinical Studies: In six clinical studies RelaxPLX® significantly: Produced less anxiety and stress in research subjects; decreased times awake; increased sleep hours, deep sleep and REM sleep.
  • Enriched with Other Natural Sleep Promoting Ingredients: In addition to RelaxPLX®, OxyNaturals®' SLEEP is enriched with other sleep-promoting nutrients including: L-tryptophan, L -ornithine, Valerian Root, Lemon Balm Extract, Ashwaagandha Root and Leaf, Hops, GABA, Magnesium (magnesium oxide, citrate and glycinate), Chamomile Extract, Passion Flower Whole Herb, L-taurine,  Magnolia Bark. Jujube Extract, Reishi Mushrooms and Melatonin. 
  • ​Take Advantage of Our Unheard of Exclusive 90-Day Risk-Free Trial Offer: We're so sure you're going to benefit greatly from OxyNaturals®' SLEEP we're confident you'll become a lifetime customer. Use 3 bottles of SLEEP for 90 days (you get one bottle FREE). If after this trial period you're not satisfied simply call us and we'll issue an immediate refund. No need to return the empty bottles.
  • Active Ingredient: SLEEP's active ingredient RelaxPLX® is produced through a patented process that extracts and purifies nutrients (phenylpropanoids/verbascoside and flavones) from the Lemon Verbena plant. RelaxPLX® has been scientifically proven to have significant benefi­cial effects on stress, anxiety and insomnia symptoms. 
  • Mechanism of Action: RelaxPLX's® mechanism of action (how it works) is in how it may affect neurotransmitters in the brain — chemicals that nerves release to communicate with other nearby nerves. One of these neurotransmitters is gamma-amino-butyric acid (GABA), a neurotransmitter that suppresses the activity of nerves. Excessive activity of nerves can be a cause of anxiety and insomnia. RelaxPLX® helps support the reduction of the activity of nerves in the brain and spinal cord by enhancing the effects of GABA and thus reducing anxiety and promoting sleep.
  • Enriched with Other Natural Sleep Promoting Ingredients: In addition to Sleep PLX®, OxyNaturals®' SLEEP is enriched with other sleep-promoting nutrients including: L-tryptophan, L -ornithine, Valerian Root, Lemon Balm Extract, Ashwaagandha Root and Leaf, Hops, GABA, Magnesium (magnesium oxide, citrate and glycinate), Chamomile Extract, Passion Flower Whole Herb, L-taurine,  Magnolia Bark. Jujube Extract, Reishi Mushrooms and Melatonin. 
  • Take Advantage of Our Unheard of Exclusive 90-Day Risk-Free Trial Offer: We're so sure you're going to benefit greatly from OxyNaturals®' SLEEP we're confident you'll become a lifetime customer. Use 3 bottles of SLEEP for 90 days (you get one bottle FREE) . If after this trial period you're not satisfied simply call us and we'll issue an immediate refund. No need to return the empty bottles.
  • Proven in 6 Clinical Studies: In six clinical studies RelaxPLX® significantly: Produced less anxiety and stress in research subjects; decreased times awake; increased sleep hours, deep sleep and REM sleep.

Powerful Key Stress, Anxiety & Sleep Ingredients in Lemon Verbena Identified, Isolated and Unlocked

The RelaxPLX® scientists, through 7 years of research and development, identified and isolated the key phytochemicals (phenylpropanoids/verbascoside and flavones) in the Lemon Verbena plant that delivered the desired anti-stress/anxiety and sleep benefits.

Then they developed a patent-pending process to unlock, extract and compound the phenylpropanoids/verbascoside and flavones to make them hundreds of times more powerful and effective than the whole powdered Lemon Verbena plant.

Does RelaxPLX® Really Work?

Before RelaxPLX® was made commercially available, it went through 15 years of development,  and it was the subject of 6 clinical trials whose results were published in 15 scientific journals. Here's a sampling of two clinical studies that support RelaxPLX®'s efficacy:

Elucidation of the Molecular Mechanism Underlying Lippia citriodora-Induced Relaxation and Anti-Depression

The International Journal of Molecular Science , July 2019.
​https://pubmed.ncbi.nlm.nih.gov/31330819/

Study Conclusion:

Findings indicate that Verbena ethanolic extract/Verbascoside (RelaxPLX®) induces relaxation and anti-depression effects by enhancing the expression of serotonin, noradrenalin, dopamine and Brain-derived neurotrophic factor (BDNF)

Anxiolytic Effect of Improved Sleep Quality in Individuals Taking Lippia Citriodora Extract (RelaxPLX®)

Nutrients, January 2022
https://pubmed.ncbi.nlm.nih.gov/35011093/

Study Conclusion:

A double-blind, placebo-controlled study was conducted for 8 weeks, followed by a 4-weeks of not taking RelaxPLX® (washout period). As a result, the group taking RelaxPLX® significantly reduced their perception of stress after 8 weeks, which was corroborated by a significant decrease in cortisol levels. After the washout period, the subjects presented even lower stress levels, due to the lasting effect of the RelaxPLX®. As for sleep quality, the subjects taking the supplement reported feeling better rested. RelaxPLX® users improved their times in the deeper stages of sleep, specifically their percentage of time in deep sleep and REM. In conclusion, RelaxPLX was revealed as a natural solution to help individuals to improve their stress and sleep quality.

In the research, RELAXPLX'S mechanism of action worked on the same neurons as prescription sleep pharmaceuticals but without addiction, side effects or morning hangover.

In the research, RelaxPLX's mechanism of action worked on the same neurons as prescription sleep pharmaceuticals but without addiction, side effects or morning hangover.

What the studies showed

OxyNaturals® SLEEP's active ingredient RelaxPLX® is safe and was well tolerated by the participants in the clinical studies. Studies show that RelaxPLX® significantly reduces stress and anxiety and promotes quick and deep sleep with fewer interruptions than those who didn't take RelaxPLX®.

OxyNaturals® SLEEP: Your All-Natural
Solution for Anxiety, Stress & Insomnia

SLEEP's active ingredient, RelaxPLX®, is a proprietary, patented botanical based on isolated and compounded full-spectrum phytochemicals extracted from the Lemon Verbena plant. These patented phytochemicals are the agents in Lemon Verbena that give it its ability to prove effective in treating anxiety, stress and insomnia.

OxyNaturals® SLEEP contains a perfect synergistic blend of the highest quality ingredients available for potency and effectiveness. In addition to RelaxPLX®, OxyNatural's SLEEP is enriched with other sleep-promoting nutrients including: L-tryptophan, L -ornithine, Valerian Root, Lemon Balm Extract, Ashwagandha Root and Leaf, Hops, GABA, Magnesium (magnesium oxide, citrate and glycinate), Chamomile Extract, Passion Flower Whole Herb, L-taurine, Magnolia Bark. Jujube Extract, Reishi Mushrooms and Melatonin.

SLEEP is non-habit forming. It has no side effects, and there's no risk of dependency. SLEEP is made in the USA in an FDA-inspected facility for quality you can trust. In addition, SLEEP is vegan and gluten-free.

Description of SLEEP's Key Relaxation
& Sleep Inducing Ingredients

SLEEP's proprietary and exclusive blend of all-natural nutraceuticals was formulated to alleviate anxiety and stress and promote deep, reparative and rejuvenating sleep. Here’s the perfect synergistic blend of ingredients in OxyNaturals® SLEEP:

Patented RelaxPLX® works through a triple-action approach to first reduce anxiety/stress, relax your body and then ease you into a deep, long-lasting sleep. It's backed by 6 clinical studies and works in the same way as insomnia pharmaceuticals with no side effects, no morning hangover and no dependency. The studies concluded that RelaxPLX® s significantly improved the quality of life through reduced anxiety/stress and better, deeper and long-lasting sleep. The studies also showed that RelaxPLX increased the relaxation, mood-enhancing and sleep-inducing neurotransmitters Serotonin, Noradrenaline / Norepinephrine, and Dopamine.

Tryptophan is an essential amino acid for general growth and development, producing niacin and creating serotonin in the body. Serotonin produces healthy sleep and a stable mood which is why high concentrations of tryptophan in turkey is sometimes attributed to making people sleepy.

L-ornithine is an essential amino acid that helps improve the quality of sleep quality. It most impacts the ability to fall asleep and stay asleep. L-ornithine not only helps you sleep easier through the night, it also helps you sleep longer.

Valerian is an herb that aids sleep as a result of its calming properties. This herb is often referred to as “nature’s Valium,” and people have used it since the Middle Ages to treat sleep disorders such as insomnia. What’s more, Valerian may help you relax and may have benefits for people who experience anxiety and stress.

An analysis has shown that rosmarinic acid, which is highly concentrated in fresh lemon balm and lemon balm extract, is the major compound responsible for GABA activity of this herb. It plays a major role by inhibiting GABA transaminase (GABA-T) and increasing GABA levels, which are responsible for reducing neuronal activity and preparing the body to get restful sleep.

The "king" of ancient Indian medicine, Ashwagandha (Withania somnifera), also known as “Indian Winter cherry” or Indian Ginseng,” is an evergreen shrub. A clinical trial concluded it can decrease stress and anxiety by 69%, improve your ability to sleep through the night by 71%, increase daytime energy by 53% and improve concentration by 50%.

The dried, flowering part of the hops plant is used to make medicine. The hop is a sedative plant. The mechanism of action of the resin of hop consists of increasing the activity of the neurotransmitter GABA, inhibiting the central nervous system. Hops in combination with Valerian and passionflower may be an effective alternative to prescription sleep medicine. A recent study compared the sleeping pill Ambien (zolpidem) to an herbal combination of hops, Valerian, and passionflower, and both were found to be equally effective.

Gamma-aminobutyric acid (GABA) is an amino acid and neurotransmitter that reduces the activity of brain cells. GABA supplements may make it easier to fall asleep by reducing cortisol and thus reducing anxiety. Stress and anxiety can interfere with sleep and have been associated with low levels of GABA. GABA may also increase the duration of uninterrupted sleep.

Chamomile is commonly regarded as a mild tranquilizer or sleep inducer. Its calming effects may be attributed to an antioxidant called apigenin. Apigenin binds to specific receptors in your brain that may decrease anxiety and initiate sleep. The use of chamomile extract can significantly improve sleep quality among elderly people. One study of 60 elderly people that compared placebo capsules to capsules of a standardized chamomile extract found the chamomile group had significantly improved sleep quality compared to the control group.

The "king" of ancient Indian medicine, Ashwagandha (Withania somnifera), also known as “Indian Winter cherry” or Indian Ginseng,” is an evergreen shrub. A clinical trial concluded it can decrease stress and anxiety by 69%, improve your ability to sleep through the night by 71%, increase daytime energy by 53% and improve concentration by 50%.

Passionflower (Passiflora incarnata), a beautiful, fast-growing perennial flower native to the Americas, is used to calm free-running thoughts in individuals with insomnia. Passionflower acts as a sedative to help treat sedative, insomnia, anxiety, and nervousness. Controlled trials conclude that passionflower acts on the central nervous system. It temporarily binds to the GABA receptors in the brain to relax the body.

L-taurine is an amino acid that calms the nervous system by facilitating the production of the neurotransmitter GABA and reducing cortisol. By helping to raise GABA levels, taurine will allow your body to manage anxiety so that your thoughts spiral out of control and you don’t get the associated cortisol and adrenaline spikes that go with anxiety and stress. As a result, L-taurine helps abolish stress, calm the nervous system, and helps you sleep better.

Magnolia bark contains honokiol, an extensively researched, highly active extract that naturally supports a sense of calm, helps balance stress responses, and promotes relaxation. Studies show that honokiol also gives you deep, restful, reparative sleep and is shown in studies to promote powerful natural calming and sleep rejuvenating benefits to work immediately, relaxing muscles throughout the body and promoting the release of mental and physical tension.

Jujube is a shrub native to Asia. The fruit, seeds and bark of the wild jujube have all been used in traditional medicine for thousands of years Wild jujube extract contains compounds that help reduce stress. The extract can help balance out hormone levels, leading to a more relaxed state. The antioxidants in jujube can help protect the body from long-term exposure to stress hormones. Jujube offers sedative effects which can help soothe anxiety and restlessness and help you to get a good, natural, drug-free night’s sleep.

Reishi mushrooms may help improve sleep quantity and quality without causing you to feel drowsy or groggy the next day. Reishi contains compounds that may help regulate your body’s stress response to improve sleep naturally. Reishi may increase sleep time. Reishi positively impacts the hypothalamus region, the portion of the brain that regulates sleep cycles, to work immediately, relaxing muscles throughout the body and promoting the release of mental and physical tension.

Melatonin is a hormone that regulates the body’s circadian rhythms. The pineal gland produces melatonin. During daytime hours, the retinas in the eyes absorb light, which tells the pineal gland to stop releasing melatonin. As the sun sets, the decrease in light signals melatonin production. Melatonin signals to the body that it is time to go to sleep and promotes the sleep state.

Patented RelaxPLX® works through a triple-action approach to first reduce anxiety/stress, relax your body and then ease you into a deep, long-lasting sleep. It's backed by 6 clinical studies and works in the same way as insomnia pharmaceuticals with no side effects, no morning hangover and no dependency. The studies concluded that RelaxPLX® s significantly improved the quality of life through reduced anxiety/stress and better, deeper and long-lasting sleep. The studies also showed that RelaxPLX® increased the relaxation, mood-enhancing and sleep-inducing neurotransmitters Serotonin, Noradrenaline / Norepinephrine, and Dopamine.

Tryptophan is an essential amino acid for general growth and development, producing niacin and creating serotonin in the body. Serotonin produces healthy sleep and a stable mood which is why high concentrations of tryptophan in turkey is sometimes attributed to making people sleepy.

L-ornithine is an essential amino acid that helps improve the quality of sleep quality. It most impacts the ability to fall asleep and stay asleep. L-ornithine not only helps you sleep easier through the night, it also helps you sleep longer.

Valerian is an herb that aids sleep as a result of its calming properties. This herb is often referred to as “nature’s Valium,” and people have used it since the Middle Ages to treat sleep disorders such as insomnia. What’s more, Valerian may help you relax and may have benefits for people who experience anxiety and stress.

An analysis has shown that rosmarinic acid, which is highly concentrated in fresh lemon balm and lemon balm extract, is the major compound responsible for GABA activity of this herb. It plays a major role by inhibiting GABA transaminase (GABA-T) and increasing GABA levels, which are responsible for reducing neuronal activity and preparing the body to get restful sleep.

The "king" of ancient Indian medicine, Ashwagandha (Withania somnifera), also known as “Indian Winter cherry” or Indian Ginseng,” is an evergreen shrub. A clinical trial concluded it can decrease stress and anxiety by 69%, improve your ability to sleep through the night by 71%, increase daytime energy by 53% and improve concentration by 50%.

The dried, flowering part of the hops plant is used to make medicine. The hop is a sedative plant. The mechanism of action of the resin of hop consists of increasing the activity of the neurotransmitter GABA, inhibiting the central nervous system. Hops in combination with Valerian and passionflower may be an effective alternative to prescription sleep medicine. A recent study compared the sleeping pill Ambien (zolpidem) to an herbal combination of hops, Valerian, and passionflower, and both were found to be equally effective.

Gamma-aminobutyric acid (GABA) is an amino acid and neurotransmitter that reduces the activity of brain cells. GABA supplements may make it easier to fall asleep by reducing cortisol and thus reducing anxiety. Stress and anxiety can interfere with sleep and have been associated with low levels of GABA. GABA may also increase the duration of uninterrupted sleep.

Chamomile is commonly regarded as a mild tranquilizer or sleep inducer. Its calming effects may be attributed to an antioxidant called apigenin. Apigenin binds to specific receptors in your brain that may decrease anxiety and initiate sleep. The use of chamomile extract can significantly improve sleep quality among elderly people. One study of 60 elderly people that compared placebo capsules to capsules of a standardized chamomile extract found the chamomile group had significantly improved sleep quality compared to the control group.

The "king" of ancient Indian medicine, Ashwagandha (Withania somnifera), also known as “Indian Winter cherry” or Indian Ginseng,” is an evergreen shrub. A clinical trial concluded it can decrease stress and anxiety by 69%, improve your ability to sleep through the night by 71%, increase daytime energy by 53% and improve concentration by 50%.

Passionflower (Passiflora incarnata), a beautiful, fast-growing perennial flower native to the Americas, is used to calm free-running thoughts in individuals with insomnia. Passionflower acts as a sedative to help treat sedative, insomnia, anxiety, and nervousness. Controlled trials conclude that passionflower acts on the central nervous system. It temporarily binds to the GABA receptors in the brain to relax the body.

L-taurine is an amino acid that calms the nervous system by facilitating the production of the neurotransmitter GABA and reducing cortisol. By helping to raise GABA levels, taurine will allow your body to manage anxiety so that your thoughts spiral out of control, and you don’t get the associated cortisol and adrenaline spikes that go with anxiety and stress. As a result, L-taurine helps abolish stress, calm the nervous system, and helps you sleep better.

Magnolia bark contains honokiol, an extensively researched, highly active extract that naturally supports a sense of calm, helps balance stress responses, and promotes relaxation. Studies show that honokiol also gives you deep, restful, reparative sleep and is shown in studies to promote powerful natural calming and sleep rejuvenating benefits to work immediately, relaxing muscles throughout the body and promoting the release of mental and physical tension.

Jujube is a shrub native to Asia. The fruit, seeds and bark of the wild jujube have all been used in traditional medicine for thousands of years Wild jujube extract contains compounds that help reduce stress. The extract can help balance out hormone levels, leading to a more relaxed state. The antioxidants in jujube can help protect the body from long-term exposure to stress hormones. Jujube offers sedative effects which can help soothe anxiety and restlessness and help you to get a good, natural, drug-free night’s sleep.

Reishi mushrooms may help improve sleep quantity and quality without causing you to feel drowsy or groggy the next day. Reishi contains compounds that may help regulate your body’s stress response to improve sleep naturally. Reishi may increase sleep time. Reishi positively impacts the hypothalamus region, the portion of the brain that regulates sleep cycles, to work immediately, relaxing muscles throughout the body and promoting the release of mental and physical tension.

Melatonin is a hormone that regulates the body’s circadian rhythms. The pineal gland produces melatonin. During daytime hours, the retinas in the eyes absorb light, which tells the pineal gland to stop releasing melatonin. As the sun sets, the decrease in light signals melatonin production. Melatonin signals to the body that it is time to go to sleep and promotes the sleep state.

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We work hard to formulate the most advanced products on the market. Our 90-Day Customer Satisfaction Guarantee is designed to give you ample opportunity to experience optimal results from OXYNATURALS® SLEEP, completely risk free.

If you're new to SLEEP and want to see if it works for you, you can use 3 bottles RISK-FREE for 90-days (Activation Phase 3 capsules per night) & Maintenance Phase (2 capsules per night). If you're not 100% satisfied, call us for a refund and dispose of the empty bottles—no need to go through the inconvenience of returning the empty bottles.

SLEEP INTRODUCTORY OFFER

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 If you purchased all of the ingredients found in SLEEP separately, you’d be paying 4 times more and taking 5 times as many pills.

IMPORTANT: Why You Need to Start With 3 Bottles

It may take up to 10-14 days for SLEEP, at 2 capsules per night, to help improve and normalize your sleeping patterns. However, it's important to give it time to work. 

Remember our 90-Day, Empty-Bottle 100% Money Back Guarantee is there to give you peace of mind to completely use the product so you can see the full benefits.

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